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Turkesterone is a natural compound found in several plants, including Ajuga turkestanica, Rhaponticum carthamoides, and Leuzea carthamoides. It is classified as an ecdysteroid, a type of steroid hormone found in insects and plants. Turkesterone has gained attention in recent years for its potential health benefits, particularly in the area of athletic performance and muscle growth. But how exactly does turkesterone work?

  1. Increased protein synthesis

One of the primary ways that turkesterone works is by increasing protein synthesis in muscle cells. Protein synthesis is the process by which cells build new proteins, and it is essential for muscle growth and repair. Turkesterone has been found to increase protein synthesis in muscle cells, leading to an increase in muscle mass and strength.

  1. Activation of mTOR signaling

Turkesterone has also been found to activate the mammalian target of rapamycin (mTOR) signaling pathway. This pathway plays a key role in regulating cell growth and metabolism, and it is particularly important for muscle growth. Activation of mTOR signaling by turkesterone can lead to increased muscle protein synthesis and cell growth.

  1. Increased heat-shock protein production

Turkesterone has been found to increase the production of heat-shock proteins (HSPs). HSPs are a family of proteins that are produced in response to stress, such as exercise. They play a key role in protecting cells from damage and promoting cell survival. Increased production of HSPs by turkesterone can lead to improved recovery after exercise and increased resistance to stress.

  1. Regulation of gene expression

Turkesterone has been found to regulate the expression of certain genes involved in muscle growth and metabolism. For example, it has been found to upregulate the expression of genes involved in protein synthesis and downregulate the expression of genes involved in muscle breakdown. This can lead to an overall increase in muscle mass and strength.

In conclusion, turkesterone works by increasing protein synthesis, activating mTOR signaling, increasing HSP production, and regulating gene expression. These mechanisms can lead to improved athletic performance, muscle growth, and recovery after exercise.